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Why should you avoid grapefruit juice while taking xanax?

Answers:1   |   LastAnswerAt:2010.10  

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visitor
Dr. Greenthumb is famous 
Asked at 2010.10.13 00:43:49
it says it on the bottle and I'm curious.
answer daddyrx  Answered at 2010.10.13 00:43:49
There is an enzyme in grapefruits and some other citrus fruits (furanocumarin) which inhibits the CYP3A4 pathway for benzodiazepine metabolism.
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